“Most coughs disappear within a few weeks, no matter what you do,” says Olveen Carrasquillo, MD, the chief of the division of internal medicine at the University of Miami Miller School of Medicine. So how can you get a much-needed break from a stubborn cough? A cough can be uncomfortable and annoying when you are trying to get through your day, and a cough that acts up at night can also disrupt your sleep. When you’re dealing with a cough, that itch in your throat can crop up at the worst times.